Table 2.
Frequencies of alleles and genotypes for CD14 rs2569190 polymorphism in septic shock patients compared to Iberian populations in Spain from 1000 Genomes Project data (http://www.1000genomes.org/1000-genomes-browsers) and SIRS patients.
| SNP | IBS population | SIRS patients | Septic shock patients | p-value(a) | p-value(b) | |
|---|---|---|---|---|---|---|
| No. | 107 | 259 | 205 | |||
| HWE (p-value) | 0.149 | 0.768 | 0.238 | |||
| Alleles | G | 51.4% | 51.2% | 48.8% | 0.939 | 0.660 |
| A | 48.6% | 48.8% | 51.2% | — | — | |
| Genotypes | AA | 29.9% | 24.1% | 28.5% | 0.235 | 0.765 |
| AG | 43.0% | 49.4% | 45.9% | 0.294 | 0.629 | |
| GG | 27.1% | 26.5% | 25.9% | 0.988 | 0.812 |
P-values were calculated by Chi-squared test: (a) differences between IBS population and septic shock patients; (b) differences between SIRS patients and septic shock patients.
Abbreviations: SIRS, patients with systemic inflammatory response syndrome; IBS, Iberian populations in Spain; HWE, Hardy-Weinberg equilibrium; CD14, cluster of differentiation 14.