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Comparison of IC50 values of classic β-lactamase inhibitors IC50 values of tazobactam, sulbactam, and clavulanic acid measured by the printed hydrogel assay relative to the conventional solution assay and reported literature values
| β-Lactamase inhibitor | IC50 (μM) | ||
|---|---|---|---|
| Printed hydrogel assay | Solution assay | Literature52 | |
| Tazobactam | 0.07 ± 0.01 | 0.06 ± 0.01 | 0.04 |
| Sulbactam | 4.1 ± 0.2 | 4.0 ± 0.3 | 6.1 |
| Clavulanic acid | 0.15 ± 0.01 | 0.19 ± 0.01 | 0.09 |
Values are represented as mean ± SD (n = 3)
