Table 3.
Down-regulation of S. aureus genes encoding major virulence factors.
| Virulence factors | Genes | Fold change (UM-C162-treated vs control) |
|---|---|---|
| Hemolysins/leukocidin | hlgA | −3.63 |
| hlgB | −4.52 | |
| hlgC | −6.61 | |
| SAOUHSC_02708 | −3.63 | |
| Phospholipase C | hlb | −2.31 |
| Serine protease (V8 protease) | sspA | −2.07 |
| Staphylococcal superantigen-like (SSL) proteins | SAOUHSC_00383 | −2.05 |
| SAOUHSC_00386 | −2.78 | |
| SAOUHSC_01127 | −2.13 | |
| Immunoglobulin-binding protein | sbi | −3.09 |
| S. aureus surface protein A | sasA | −2.84 |
| S. aureus exoprotein expression protein | saeR | −2.9 |