Table 1.

Parameter values in the Markov model with associated literature references where appropriate. Probabilities of support after surgery and costs associated with shunt surgery are based on data assessed in this study

Parameter	Value	Statistics/rangea	Distribution	Reference
Probabilities first year
Being improved	0.73		Beta	[43]
Complication	0.15		Beta	[11]
Being deteriorated	0.10		Beta	[25]
Probabilities after first year
Complication	0.02		Beta	[11]
Being improved after complication	0.70		Beta	[2]
Being deteriorated	0.10		Beta	[25]
Annual mortality rate, deteriorated	0.10		Beta	[2]
Probabilities of support after surgery
Living at residential care	0.07 (2 out of 30)		Uniform
Home service	0.23 (7 out of 30)		Uniform
Informal support	0.60 (18 out of 30)		Uniform
Probabilities of support, natural history			Uniform
Living in residential care	0.42		Uniform	[35]
Day care	0.06		Uniform	[35]
Cost (€)
Surgery	10,200	8,160–12,240	Gamma
Inpatient care	3,900	3,120–4,680	Gamma
Outpatient care	1,700	1,360–2,040	Gamma
Living in residential care	60,600	48,480–72,720	Gamma	[35]
Home service, after surgery	5,200	4,160–6,240	Gamma	[35]
Home service, natural history	6,900
Day care, natural history	9,900		Gamma	[35]
Informal support, after surgery	6,600	5,280–7,920	Gamma
Informal support, natural history	10,500			[35]
QALY-weights (mean)
Improved	0.71	0.57–0.85	Beta	[31]
Complication, deteriorated, natural history	0.57	0.46–0.68	Beta	[31]
Discount rate (%)	3	0–5

Costs are presented as annual cost per patient

^aRange ± 20%