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. 2018 Feb 9;8:2714. doi: 10.1038/s41598-018-21056-y

Table 5.

Ki and IC50 values of PmDAP IV and human DPP IV for diprotin A.

Enzyme Residual activity (%) Ki (µM) IC50 (µM)
PmDAP IV wild-type 3.45 ± 0.10# 0.474 ± 0.020 2.91 ± 0.12
PmDAP IV R106A 7.63 ± 0.12 1.57 ± 0.26 7.41 ± 1.24
PmDAP IV R106K 8.17 ± 0.06 2.36 ± 0.11 9.19 ± 0.45
Human DPP IV 13.7 ± 0.8 4.01 ± 0.30 14.8 ± 1.1

#Standard deviation obtained from three independent experiments.