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. 2018 Feb 5;9:160. doi: 10.3389/fimmu.2018.00160

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Copyright © 2018 Liu, Zhu, Qian, Xiong, Zhang, Wang, Chu, Kubagawa, Tsubata and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Marginal zone B cells (MZB) development in 3-, 6-, and 9-week-old WT and FcμR^−/− mice. (A) Fc receptor (FcμR) expression at different stages of MZB development. MFI ± SD of the results from four 8- to 10-week-old mice are shown. MFI of the B220⁻ cells was set to 1. (B) The proportion of T1 and T2 in 3-, 6-, and 9-week-old WT and FcμR^−/− mice (n = 3 or 4). (C) The proportion of marginal zone precursor (MZP), MZB, and follicular B (FOB) in 3-, 6-, and 9-week-old WT and FcμR^−/− mice (n = 3 or 4). The gating strategy is shown in Figure S1 in Supplementary Material. *p < 0.05; **p < 0.01.