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. 2018 Feb 5;9:160. doi: 10.3389/fimmu.2018.00160

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Copyright © 2018 Liu, Zhu, Qian, Xiong, Zhang, Wang, Chu, Kubagawa, Tsubata and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Increased death and turnover in marginal zone B cells (MZB) of FcμR^−/− mice. (A) The proportion of 7AAD⁺ dead cells in gated MZB and follicular B (FOB) in the spleen. (B) Increased proportion of Casp3⁺ MZB in FcμR^−/− mice. (C) Increased EdU⁺ marginal zone precursor (MZP) and MZB population in FcμR^−/− mice. (D) Proportion of EdU⁺ cells at each stage of MZB development. Mean ± SD of the results from three to four mice are shown. For panels (B–D), 10- to 12 week-old mice were analyzed. *p < 0.05; **p < 0.01.