Figure 2.

Representative horizontal leftward saccade before (A) and after Dalfampridine (B) in one patient. (A) Particularly for the leftward movement the adducting eye requires several small saccades to acquire the target (arrows) and the abducting eye shows dissociated nystagmus. (B) The right eye requires less adducting saccades to acquire the target (arrows) and dissociated nystagmus intensity is decreased. Positive values indicate rightward movements, negative values indicate leftward movements. *Adapted with permission from Ref. (49).