Table 3.
Dosimetric comparison between PBT and 3DCRT, PBT and IMRT
| End point | DVH parameters | Technique | Mean | SD | SE mean |
p value. (vs. 3DCRT) |
p value. (vs. IMRT) |
|---|---|---|---|---|---|---|---|
| Lung | V20 (%) | PBT | 11.6607 | 5.18604 | .99805 | .001 | < 0.01 |
| 3DCRT | 16.9652 | 5.64638 | 1.08665 | ||||
| IMRT | 17.7941 | 5.19620 | 1.00001 | ||||
| V15 (%) | PBT | 17.8696 | 7.22321 | 1.39011 | .052 | .006 | |
| 3DCRT | 21.6615 | 6.75645 | 1.30028 | ||||
| IMRT | 22.9630 | 5.64911 | 1.08717 | ||||
| V10 (%) | PBT | 21.3307 | 9.07254 | 1.74601 | .058 | < 0.01 | |
| 3DCRT | 25.7222 | 7.46624 | 1.43688 | ||||
| IMRT | 30.0181 | 6.84990 | 1.31826 | ||||
| V5 (%) | PBT | 25.2478 | 10.77897 | 2.07441 | .005 | < 0.01 | |
| 3DCRT | 33.0893 | 8.79872 | 1.69331 | ||||
| IMRT | 45.1811 | 10.52645 | 2.02582 | ||||
| Mean dose (Gy) | PBT | 5.8322 | 2.24148 | .43137 | < 0.01 | < 0.01 | |
| 3DCRT | 8.2111 | 2.14654 | .41310 | ||||
| IMRT | 9.4778 | 2.17052 | .41772 | ||||
| Heart | V40 (%) | PBT | 16.3059 | 11.42262 | 2.19828 | < 0.01 | 0.012 |
| 3DCRT | 48.1837 | 21.03337 | 4.04787 | ||||
| IMRT | 26.5770 | 16.91562 | 3.25541 | ||||
| V30 (%) | PBT | 22.0252 | 14.45506 | 2.78188 | < 0.01 | < 0.01 | |
| 3DCRT | 56.1574 | 21.49217 | 4.13617 | ||||
| IMRT | 50.7126 | 23.40755 | 4.50479 | ||||
| V20 (%) | PBT | 38.4963 | 23.91227 | 4.60192 | < 0.01 | < 0.01 | |
| 3DCRT | 64.1178 | 23.03079 | 4.43228 | ||||
| IMRT | 69.3259 | 26.97548 | 5.19143 | ||||
| Mean dose (Gy) | PBT | 17.6089 | 9.68207 | 1.86331 | < 0.01 | .001 | |
| 3DCRT | 30.9844 | 11.45297 | 2.20412 | ||||
| IMRT | 9.4778 | 2.17052 | .41772 | ||||
| Spinal cord | Maximum dose (Gy) | PBT | 38.1400 | 4.96680 | .95586 | < 0.01 | .155 |
| 3DCRT | 47.2896 | 2.22998 | .42916 | ||||
| IMRT | 39.7119 | 2.64873 | .50975 | ||||
| CI | PBT | 1.8796 | .21319 | .04103 | < 0.01 | < 0.01 | |
| 3DCRT | 3.1886 | .61704 | .11875 | ||||
| IMRT | 1.6243 | .23493 | .04521 |
SD standard deviation, SE standard error, CI conformity index