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FXR model complexed with 6 and 10. (A) Complex model of hFXRα-LBD homodimer (PDB ID: 4OIV, blue wires and green ribbons) with 10 (yellow) and 6 (pink) was built using AutoDock Vina1.1.2. (B) Hydrogen bond between the carbonyl group on piperidine of 10 and His298 (yellow dashed line).
