Table 1.
Differentially expressed genes (|log2FC| ≥ 5) between periodontitis and laboratory culture in Porphyromonas gingivalis.
| Genes | log2FC | log2CPM | FDR | Product | Gene |
|---|---|---|---|---|---|
| PG1019 | 7.555157 | 10.38787 | 3.62E-21 | Putative lipoprotein | |
| PG1181 | 7.218641 | 8.524394 | 1.04E-14 | TetR family transcriptional regulator | – |
| PG0222 | 7.084658 | 6.081433 | 0.005578 | Histone-like family DNA-binding protein | – |
| PG2133 | 6.637346 | 8.215433 | 2.21E-12 | Putative lipoprotein | – |
| PG1551 | 6.38076 | 11.65887 | 1.36E-18 | HmuY protein | hmuY |
| PG2134 | 6.343568 | 8.924579 | 7.13E-16 | Putative lipoprotein | – |
| PG1552 | 6.328257 | 10.56244 | 4.71E-17 | TonB-dependent receptor HmuR | hmuR |
| PG1554 | 6.146314 | 6.953868 | 4.43E-07 | HmuT | hmuT |
| PG1555 | 5.922429 | 6.856549 | 7.01E-06 | HmuU | hmuU |
| PG1556 | 6.029691 | 6.654237 | 2.54E-07 | HmuV | hmuV |
| PG1858 | 6.310506 | 11.24736 | 3.07E-17 | Flavodoxin FldA | – |
| PG1553 | 6.011982 | 10.89276 | 4.43E-16 | CobN/magnesium chelatase, HmuS | hmuS |
| PG1055 | 5.721684 | 10.13226 | 9.86E-07 | Thiol protease | tpr |
| PG2008 | 5.571255 | 11.36346 | 3.74E-11 | TonB-dependent receptor | – |
| PG1467 | 5.118896 | 7.279726 | 3.46E-08 | UbiE/COQ5 family methlytransferase | – |
| PG2132 | 5.010408 | 9.743426 | 4.43E-07 | Fimbrilin | fimA |
| PG0850 | -6.94149 | 3.985838 | 0.038459 | Excisionase DNA-binding protein | – |
| PG2135 | -6.96172 | 4.009491 | 0.037717 | Putative lipoprotein | – |
| PG0225 | -7.08273 | 4.105006 | 0.030378 | ISPg4, transposase | – |
| PG0019 | -7.2357 | 4.202793 | 0.020536 | ISPg4 transposase | – |
| PG1515 | -7.44897 | 4.384304 | 0.012294 | Ribulose bisphosphate carboxylase-like protein | – |
| PG2038 | -7.59084 | 4.510893 | 0.027908 | N-acetylmuramoyl-L-alanine amidase | – |
| PG1514 | -7.64219 | 4.534787 | 0.008586 | Glycerol dehydrogenase | – |
| PG1436 | -7.92391 | 4.752115 | 0.003722 | ATPase | – |
| PG1513 | -8.29828 | 5.043848 | 0.000698 | Phosphoribosyltransferase/phosphoglycerate mutase | – |
| PG1531 | -8.99779 | 5.613199 | 5.57E-05 | ||
| PG0860 | -9.05442 | 5.655394 | 7.22E-05 | Transcriptional regulator | – |
| PG0838 | -10.0629 | 6.518683 | 2.79E-07 | Integrase | – |
| PG0971 | -10.1306 | 6.573451 | 2.48E-07 | McrBC restriction endonuclease system, McrB subunit | – |
| PG0110 | -10.4796 | 6.887122 | 2.19E-07 | Glycosyl transferase | – |
| PG0544 | -10.5353 | 6.934028 | 1.49E-08 | Type I restriction-modification system, M subunit | – |
| PG0111 | -10.7694 | 7.142878 | 9.11E-09 | Capsular polysacharride biosynthesis gene | – |
| PG2016 | -11.2452 | 7.56776 | 1.37E-09 | CRISPR-associated helicase Cas3 | cas3 |
| PG0862 | -11.6934 | 7.978136 | 1.06E-13 | Type IIS restriction endonuclease | – |
| PG0861 | -11.7768 | 8.055359 | 9.12E-15 | Snf2/Rad54 family helicase | – |
| PG0742 | -12.0578 | 8.317474 | 1.59E-17 | Antigen PgaA | pgaA |