Table 5.
Differentially expressed genes (15 most up- and down-regulated in periodontal pocket) between periodontitis and laboratory culture in Fusobacterium nucleatum.
| Genes | log2FC | log2CPM | FDR | Product |
|---|---|---|---|---|
| 992844 | 8.017376 | 9.386693 | 1.02E-06 | Hemin receptor |
| 991530 | 7.958785 | 10.18326 | 3.03E-05 | Cytochrome C-type biogenesis protein CcdA |
| 992301 | 6.994423 | 9.333086 | 2.66E-08 | Sodium-dependent tyrosine transporter |
| 993078 | 6.637803 | 10.87725 | 6.30E-05 | Thiol:disulfide interchange protein TlpA |
| 992331 | 6.282339 | 12.31312 | 8.09E-10 | Acyl-CoA dehydrogenase |
| 992475 | 6.080619 | 10.48263 | 2.66E-08 | 168 kDa surface-layer protein |
| 993221 | 5.992068 | 7.534582 | 2.01E-07 | Na(+)-linked D-alanine glycine permease |
| 992567 | 5.841546 | 8.935339 | 0.000108 | ABC transporter |
| 992565 | 5.693574 | 8.578332 | 0.000561 | ABC transporter |
| 992642 | 5.658047 | 4.802479 | 9.15E-05 | Pyruvate-flavodoxin oxidoreductase |
| 993083 | 5.352238 | 12.57303 | 0.001161 | Bifunctional methionine sulfoxide reductase A/B protein |
| 992564 | 5.321549 | 7.156876 | 0.001161 | Flavodoxin |
| 992833 | 5.064472 | 1.627067 | 0.022785 | Crp/Fnr family transcriptional regulator |
| 992566 | 5.046786 | 4.002014 | 0.006948 | Cytoplasmic protein |
| 993227 | -12.2841 | 5.180294 | 0.002829 | Glucosamine–fructose-6-phosphate aminotransferase |
| 991497 | -12.5217 | 5.210201 | 0.000697 | DNA-dependent DNA polymerase III subunit alpha |
| 991244 | -12.6182 | 5.220475 | 0.000149 | ABC transporter ATP-binding protein |
| 992659 | -13.7519 | 6.117626 | 2.87E-05 | RNA-directed DNA polymerase |
| 992085 | -14.0511 | 6.357712 | 1.26E-05 | MunI regulatory protein |
| 991246 | -14.9509 | 7.183505 | 0.000375 | Heteropolysaccharide repeat-containing protein |
| 991329 | -15.0455 | 7.223317 | 4.88E-05 | UDP-N-acetyl-D-quinovosamine 4-epimerase |
| 992734 | -15.1044 | 7.236464 | 1.09E-06 | Quinovosaminephosphotransferae |
| 992744 | -15.1989 | 7.412729 | 0.00056 | Glycosyl transferase |
| 991554 | -15.2229 | 7.479123 | 0.001161 | Acetyltransferase |
| 991291 | -15.2735 | 7.360318 | 3.18E-07 | Cysteine desulfurase NifS |
| 992796 | -15.848 | 7.846506 | 3.57E-08 | Spore coat polysaccharide biosynthesis protein SpsF |
| 992371 | -15.8759 | 7.966607 | 0.000219 | DNA helicase |
| 991799 | -16.1556 | 8.205795 | 0.000185 | dTDP-4-dehydrorhamnose reductase |
| 991238 | -18.7406 | 10.56156 | 6.06E-05 | LPS biosynthesis protein WbpG |