Boxplots for (A) the radius, (B) the porosity, (C) the branch length, and (D) the tortuosity of the microcirculation as function of TAA intoxication time and location within the lobe. Slices (350 μm) were taken near the top (up to 2 mm from the surface) and mid (4–6 mm from the surface) region of the right medial lobe (RML). Sinusoids situated in the core of the lobe appeared to be less affected by the cirrhogenic process, as their mean radii and porosity were typically larger than those near the surface. When comparing the 18‐week intoxicated samples pairwise, the radii differed significantly between the top and mid region (P = 0.048).