. 2018 Jan 9;232(3):472–484. doi: 10.1111/joa.12773

Table 1.

Stereological parameters for the assessment of lung architecture in individual lung lobes, and in whole, intact lungs, in mice at post‐natal day 14 with normal lung development

Parameter				Lobus Cranialis			Lobus Medius			Lobus Caudalis			Lobus Cardialis			Lobus Sinister			Intact Lung
				Mean (SD)			Mean (SD)			Mean (SD)			Mean (SD)			Mean (SD)			Mean (SD)
V (lobe) [cm³]		V (lung) [cm³]		0.0414 (0.0056)			0.0272 (0.0030)			0.0582 (0.0092)			0.0276 (0.0074)			0.0846 (0.0149)			0.2410 (0.0299)
CE	CV		CE²/CV²	0.055	0.136	0.167	0.045	0.110	0.167	0.065	0.159	0.167	0.109	0.266	0.167	0.072	0.176	0.167	0.056	0.124	0.200
V _V (par/lobe) [%]		V _V (par/lung) [%]		0.9255 (0.0229)			0.9055 (0.0227)			0.8968 (0.0237)			0.8897 (0.0244)			0.9073 (0.0194)			0.8920 (0.0561)
CE	CV		CE²/CV²	0.010	0.025	0.167	0.010	0.025	0.167	0.011	0.026	0.167	0.011	0.027	0.167	0.009	0.021	0.167	0.028	0.063	0.200
N (alv, lobe) 10⁶		N (alv, lung) 10⁶		0.9053 (0.1689)			0.5170 (0.0706)			1.1590 (0.3913)			0.4594 (0.1707)			1.4550 (0.3408)			4.0040 (0.4198)
CE	CV		CE²/CV²	0.076	0.187	0.167	0.056	0.137	0.167	0.138	0.338	0.167	0.152	0.372	0.167	0.096	0.234	0.167	0.0469	0.1048	0.200
N _V (alv/par, lobe) 10⁷ [cm⁻³]		N _V (alv/par, lung) 10⁷ [cm⁻³]		2.3710 (0.3465)			2.1040 (0.1736)			2.0190 (0.3311)			1.8560 (0.4651)			1.8940 (0.2745)			1.8770 (0.2041)
CE	CV		CE²/CV²	0.060	0.146	0.167	0.041	0.091	0.167	0.068	0.152	0.167	0.087	0.194	0.167	0.058	0.130	0.167	0.049	0.109	0.200
S _V [cm⁻¹]		S _V (lung) [cm⁻¹]		849.40 (66.43)			793.10 (83.29)			748.80 (53.06)			769.80 (71.10)			757.00 (78.28)			802.20 (32.98)
CE	CV		CE²/CV²	0.032	0.078	0.167	0.043	0.105	0.167	0.029	0.071	0.167	0.038	0.092	0.167	0.042	0.103	0.167	0.018	0.041	0.200
S (alv epi, lung) [cm²]		S (alv epi, lung) [cm²]		32.82 (7.37)			19.39 (1.91)			39.06 (6.68)			18.61 (3.98)			58.24 (12.89)			171.70 (17.63)
CE	CV		CE²/CV²	0.092	0.224	0.167	0.040	0.099	0.167	0.070	0.171	0.167	0.087	0.214	0.167	0.090	0.221	0.167	0.046	0.103	0.200
τ (sep, lobe) [μm]		τ (sep, lung) [μm]		8.9150 (0.9215)			9.2410 (1.1210)			10.5700 (1.3310)			11.5200 (1.8650)			10.5100 (1.5960)			10.8200 (0.9956)
CE	CV		CE²/CV²	0.042	0.103	0.167	0.050	0.121	0.167	0.051	0.126	0.167	0.066	0.162	0.167	0.062	0.152	0.167	0.041	0.092	0.200
MLI (lobe) [μm]		MLI (lung) [μm]		27.7400 (3.0150)			30.3500 (5.6540)			30.5500 (5.0120)			27.5800 (3.9580)			30.7200 (4.8340)			28.3000 (0.9860)
CE	CV		CE²/CV²	0.044	0.109	0.167	0.076	0.186	0.167	0.067	0.164	0.167	0.059	0.144	0.167	0.064	0.157	0.167	0.016	0.035	0.200

alv, alveoli; alv air, alveolar airspaces; alv epi, alveolar epithelium; CE, coefficient of error; CV, coefficient of variation; l., lobus; MLI, mean linear intercept; N, number, N_V, numerical density; P, post‐natal day; par, parenchyma; S, gas‐exchange surface area; S_V, surface density; τ (sep), arithmetic mean septal thickness; V, volume; V_V, volume density. Values are presented as mean (SD), n = 5–6 lungs or lobes per group.