Table 1. Regions of kataegis affecting gene regulatory and exonic regions in individual CLL cases.
| Patient ID | IgHV status | Chr. | Start (bp) | End (bp) | No. of mutations | Affected genes |
|---|---|---|---|---|---|---|
| CLL156 | Unmutated | 2 | 140 885 911 | 141 045 820 | 8 | LRP1B |
| CLL154 | Mutated | 3 | 157 290 339 | 157 295 704 | 6 | PQLC2L |
| CLL348 | Mutated | 3 | 183 273 058 | 183 273 364 | 6 | KLHL6 |
| CLL063 | Unmutated | 5 | 21 810 369 | 21 843 504 | 9 | CDH12 |
| CLL301 | Mutated | 7 | 122 433 699 | 122 517 296 | 12 | CADPS2 |
| CLL301 | Mutated | 7 | 122 622 586 | 122 638 447 | 6 | TAS2R16 |
| CLL351 | Mutated | 9 | 123 416 699 | 123 479 606 | 43 | MEGF9 |
| CLL144 | Mutated | 11 | 108 121 624 | 108 129 499 | 9 | ATM |
| CLL307 | Unmutated | 13 | 51 664 141 | 51 665 954 | 6 | LINC00371 |
| CLL156 | Unmutated | 14 | 21 835 327 | 21 835 546 | 6 | SUPT16H |
| CLL252 | Unmutated | 18 | 9 284 149 | 9 374 417 | 6 | ANKRD12 |
| CLL301 | Mutated | 18 | 60 873 525 | 60 988 029 | 12 | BCL2 |
| CLL348 | Mutated | 18 | 60 906 440 | 60 988 117 | 10 | BCL2 |
| CLL301 | Mutated | X | 98 765 633 | 98 769 284 | 10 | XRCC6P5 |
Abbreviations: CLL, chronic lymphocytic leukaemia; IgHV, Ig variable heavy-chain locus.