Figure 11.

Effect of pistachios on adhesion molecules and nitrotyrosine and PARP co-localization. Positive co-staining of ICAM with P-selectin and nitrotyrosine with PARP increased in STZ-I/R rats during the ischemia reperfusion injury (C,D). NP reduced the number of positive cells (E,F see densitometric analysis I,L). RP provided a minor effect on co-localization of ICAM with P-selectin (G,H see densitometric analysis I,L). No positive cells were detected in sham treated animals (A,B). The pictures are indicative of at least three experiments performed on different experimental days. Images are representative of all the mice in every group. A resolution of 8 bits was used to digitalize all images into an rank of 2048 × 2048 pixels. Data are means ± S.E.M. of 10 rats for each group. ^*P < 0.05 vs. sham, °P < 0.05 vs. ischemia-reperfusion.