Table 1.
Growth and Distal Lung Development in the Presence and Absence of Tgfbi
| Postnatal age (N) | Weight (g) | MLI (μm) | Nodal density (points per mm2) |
|---|---|---|---|
| P4-WT (6) | 2.8 ± 0.3 | 68.82 ± 1.70 | 1120 ± 35 |
| P4-KO (5) | 2.6 ± 0.2 | 71.49 ± 1.80 | 1069 ± 46 |
| P7-WT (6) | 4.4 ± 0.3 | 65.03 ± 1.07 | 1393 ± 69 |
| P7-KO (5) | 4.0 ± 0.3 | 73.46 ± 0.98∗ | 1066 ± 61∗ |
| P14-WT (7) | 10.0 ± 0.7 | 54.40 ± 0.40 | 2105 ± 39 |
| P14-KO (8) | 9.7 ± 1.0 | 57.28 ± 0.91∗ | 1898 ± 56∗ |
| P28-WT (7) | 16.9 ± 1.2 | 52.61 ± 1.24 | 2153 ± 77 |
| P28-KO (6) | 14.9 ± 0.9 | 57.47 ± 1.33∗ | 1932 ± 30∗ |
| Ad-WT (4) | 29.9 ± 0.3 | 49.22 ± 0.87 | 2522 ± 41 |
| Ad-KO (4) | 29.2 ± 1.7 | 51.17 ± 0.95 | 2339 ± 33∗ |
Values are means ± SEM.
KO, knockout; MLI, mean linear intercept; WT, wild-type littermate.
∗
P < 0.05 versus WT at equivalent postnatal age.