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. 2018 Feb 6;6:5. doi: 10.3389/fcell.2018.00005

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Copyright © 2018 Chen, Laursen, Habekost, Knudsen, Buchholdt, Huang, Xu, Liu, Bolund, Luo, Nissen, Febbraro and Denham.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RNAseq profiling of ATPase expression in human embryonic stem cells and in early neural stem cell states. (A) Overview of protocol for deriving neural epithelial progenitors (NEP), and neuromesodermal progenitors (NMP) on day 4; rostral neural stem cells (NSC), neural crest stem cells (NCSCs) and caudal NSC on day 11. (B) Gene expression of known markers indicative of the various stem cell states. (C) Principal component analysis of expression of ATPases during early neural progenitor states. (D) RNAseq profiling of ATP2B1-4 expression (in RPKM values) in human embryonic stem cells and in early neural stem cell states (^****p < 0.001). Not all significant differences are indicated. Legend shown in (D) also represents colored dots in (C).

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