Table 1.
Index | Gene | Exon/targets validated |
Target# (N = 47) | |
---|---|---|---|---|
≥10 Samples tested | <10 Samples tested | |||
1 | AKT1 | 3 | 1 | |
2 | ALK | 23, 25 | 2 | |
3 | BRAF | 11, 15 | 2 | |
4 | EGFR | 18, 19,∗ 20,∗ 21 | 4 | |
5 | ERBB2 | 20∗ | 8, 19 | 3 |
6 | FGFR2 | 7, 9, 12 | 3 | |
7 | FGFR3 | 7, 9, 18 | 3 | |
8 | GNA11 | 5 | 1 | |
9 | GNAQ | 5 | 1 | |
10 | GNAS | 8 | 1 | |
11 | HRAS | 2, 3 | 2 | |
12 | IDH1 | 4 | 1 | |
13 | IDH2 | 4 | 1 | |
14 | KIT | 9, 11,∗ 13 | 17 | 4 |
15 | KRAS | 2, 3 | 4 | 3 |
16 | NRAS | 3 | 2 | 2 |
17 | PDGFRA | 18 | 12 | 2 |
18 | PIK3CA | 10, 21 | 2, 5, 8 | 5 |
19 | TP53 | 4, 5, 6,∗ 7, 8,∗ 10 | 6 | |
Total | 17 | 30 | 47 |
Samples validated for both single nucleotide variations and insertion/deletions.