Table 3.
Genes upregulated by bile in H7858 with no homolog in 10403S.
| H7858 Locus (peg_) | FC | Function | Presence ina: | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Lineage I | Lineage II | Lineage III | L. innocua | L. ivanovii | L. seeligeri | L. welshimeri | |||
| 1532 | 4.4 | N-acetylmuramic acid 6-phosphate etherase | + | – | Vk | – | + | + | + |
| 2817 | 2.7 | Transcriptional regulator2C GntR family | + | – | Vl | + | + | + | + |
| 2818 | 4.2 | Possible membrane fusion protein | + | – | Vl | + | + | + | + |
| 40 | 5.5 | Hypothetical protein | + | Vj | – | – | + | – | – |
| 2667 | 4.4 | Substrate binding periplasmic protein MalE | + | Vh | Vn | – | + | – | + |
| 2686 | 2.5 | Internalin-like protein Lin0295 homolog | + | Vi | + | + | – | + | – |
| 16 | 4.6 | Hypothetical protein | Vb | – | – | – | – | – | – |
| 17 | 5.4 | N-acetylmuramoyl-L-alanine amidase2C family | Vb | – | – | – | – | – | – |
| 18 | 4.4 | Hypothetical protein | Vb | – | – | – | – | – | – |
| 500 | 5.3 | FIG00775381: hypothetical protein | Vb | – | – | – | – | – | – |
| 962 | 4.1 | ABC transporter2C ATP-binding protein | Vc | – | – | – | – | – | – |
| 2562 | 2.6 | Membrane protein | Vb | – | – | – | + | – | – |
| 2563 | 3.0 | Glycosyltransferase | Vb | – | – | – | + | – | – |
| 296 | 3.6 | FIG00774814: hypothetical protein | Vb | – | Vm | + | – | – | + |
| 297 | 4.9 | Wall-associated protein | Vb | – | + | + | – | – | + |
| 667 | 2.9 | Reverse transcriptase | Vo | Vd | – | – | – | – | – |
| 2114 | 4.3 | Hypothetical protein | Vo | Ve | – | + | – | – | – |
| 2139 | 2.8 | Hypothetical protein | Vo | Vf | – | – | – | – | – |
| 2140 | 3.4 | Hypothetical protein | Vo | Vf | – | – | – | – | – |
| 2151 | 2.7 | Protein gp34 [Bacteriophage A118] | Vo | Vg | – | + | – | – | – |
| 2153 | 2.8 | Hypothetical protein | Vo | Vg | – | + | – | – | – |
| 2152 | 3.1 | Lin2383 protein | Vo | Vg | Vn | – | – | – | – |
| 2143 | 4.2 | Hypothetical protein | Vo | – | – | – | – | – | – |
| 2144 | 2.7 | Protein gp38 [Bacteriophage A118] | Vo | – | – | – | – | – | – |
| 2145 | 3.6 | Transcriptional regulator | Vo | – | – | – | – | – | – |
| 2147 | 4.9 | Hypothetical protein | Vo | – | – | – | – | – | – |
| 2895 | 2.6 | Hypothetical protein | Vo | – | – | – | – | – | – |
| 2896 | 2.8 | Hypothetical protein | Vo | – | – | – | – | – | – |
| 2897 | 2.6 | Hypothetical protein | Vo | – | – | – | – | – | – |
| 2898 | 2.8 | Hypothetical protein | Vo | – | – | – | – | – | – |
| 953 | 2.8 | AAA superfamily ATPase | Vo | – | – | – | – | – | + |
| 954 | 2.8 | Putative serine protease | Vo | – | – | – | – | – | + |
| 2127 | 3.5 | SAM:benzoic acid carboxyl methyltransferase | Vo | – | Vn | – | – | – | – |
Gene distribution was characterized among 27 genomes representing L. monocytogenes lineage I (n = 10), lineage II (n = 9), lineage III (n = 4), as well as other Listeria species (L. innocua, L. ivanovii, L. seeligeri, and L. welshimeri; n = 1 each). Genes absent in all genomes searched are labeled as “–”, genes present in all genomes searched are labeled as “+” and genes that showed variable presence are labeled as “V”.
Present in serotype 4b, 4d, and 4e strains. Absent from 3b, 7, and 1/2b strains.
Absent from ATCC 19117 and SLCC2540.
Present in two serotype 3a strains (Finland and SLCC7179). SLCC7179 DNA sequence has only 68% similarity and presents 48 indels in comparison to H7858 sequence.
Strains SLCC2479 (3c), SLCC2372 and FSLR2561 (1/2c), J0161 and 085923 (1/2a).
Present in strains SLCC2479 (3c) and SLCC2372 (1/2c).
Present in strains J0161 (1/2a), SLCC2479 (3c), SLCC2372 and FSLR2561 (1/2c).
Present in J0161 and 085923 (1/2a), SLCC2479 (3c), and SLCC2372 and FSLR2561 (1/2c).
Present in J0161.
Present in 4 strains (J011, SLCC7179, Finland and 085923).
Only serotype 4c strain (SLCC2376).
Present in SLCC2376.
Present in all 4a strains and absent in SLCC2376.
Present in strains 4a (M7, L99, and HCC23).
Present in H7858 only.