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. 2018 Feb 7;9:172. doi: 10.3389/fimmu.2018.00172

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Copyright © 2018 Hou, Zhou, Yu, Mao, Bosco, Wang, Lu, Mao, Wu, Wang and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The secretion of IFN-γ can reflect the function of CD4⁺, CD8⁺ T cells, and NK cells. (A) Correlation between the percentage of IFN-γ⁺ cells and the percentages of TNF-α⁺, IL-2⁺, IL-17⁺, IL-21⁺, HLA-DR⁺, CCR7⁺ cells in CD4⁺ T cells. (B) Correlation between the percentage of IFN-γ⁺ cells and the percentages of TNF-α⁺, IL-2⁺, HLA-DR⁺, CCR7⁺, CD107a⁺ cells in CD8⁺ T cells, and correlation between the percentage of IFN-γ⁺ CD8⁺ T cells and the cytotoxicity of peripheral blood mononuclear cells (PBMCs). (C) Correlation between the percentage of IFN-γ⁺ cells and the percentages of TNF-α⁺, NKG2D⁺, HLA-DR⁺, CCR7⁺, CD107a⁺ cells in NK cells, and correlation between the percentage of IFN-γ⁺ NK cells and the cytotoxicity of PBMCs. Each symbol represents an individual donor.