Table 1.
General clinical and biochemical characteristics of overweight/obese patients and normal controls.
| Normal controls (n = 40) | Overweight/obese (n = 40) | P-value | |
|---|---|---|---|
| Age (years) | 44.6 ± 8.3 | 42.8 ± 4.5 | ns |
| Gender (male/female) | 20/20 | 20/20 | ns |
| Weight (kg) | 61.2 ± 9.1 | 77.0 ± 9.7 | <0.01 |
| BMI (kg m−2) | 22.5 ± 2.6 | 28.5 ± 2.2 | <0.01 |
| Waist circumferences (cm) | |||
| Male | 83.8 ± 9.2 | 99.6 ± 10.4 | <0.01 |
| Female | 76.7 ± 6.8 | 89.5 ± 5.8 | <0.01 |
| Fat mass (kg) | |||
| Male | 21.3 ± 6.1 | 30.6 ± 5.9 | <0.01 |
| Female | 28.6 ± 4.9 | 40.0 ± 4.3 | <0.01 |
| Fasting glucose (mmol L−1) | 5.5 ± 1.1 | 6.0 ± 0.9 | <0.05 |
| Fasting insulin (mIU mL−1) | 6.2 ± 3.5 | 10.5 ± 6.9 | <0.01 |
| HOMA-IR | 1.7 ± 1.0 | 3.0 ± 2.6 | <0.05 |
| ALT (U L−1) | 24.6 ± 10.2 | 28.4 ± 11.0 | ns |
| AST (U L−1) | 21.2 ± 10.1 | 20.8 ± 5.3 | ns |
| BUN (mmol L−1) | 5.1 ± 1.2 | 5.0 ± 1.4 | ns |
| Creatinine (μmol L−1) | 73.1 ± 23.8 | 82.0 ± 26.4 | ns |
| Uric acid (μmol L−1) | 252.2 ± 98.6 | 289.4 ± 96.4 | ns |
| SBP (mmHg) | 113.8 ± 19.3 | 120.3 ± 13.4 | ns |
| DBP (mmHg) | 76.0 ± 12.5 | 81.9 ± 9.5 | <0.05 |
| TC (mmol L−1) | 4.5 ± 1.1 | 4.8 ± 0.8 | ns |
| TG (mmol L−1) | 2.1 ± 2.8 | 2.6 ± 2.0 | ns |
| HDL-C(mmol L−1) | 1.9 ± 0.5 | 1.3 ± 0.4 | ns |
| LDL-C (mmol L−1) | 2.7 ± 0.7 | 3.0 ± 0.7 | ns |
| ZAG (μg mL−1) | 50.1 ± 9.0 | 38.3 ± 11.4 | <0.01 |
BMI, body mass index; HOMA-IR, homeostasis model assessment estimate of insulin resistance; ALT, alanine transaminase; AST, aspartate transaminase; BUN, blood urea nitrogen; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ZAG, zinc-α2-glycoprotein. Data are shown as the mean ± s.d.