Figure 4.

Differences in expression of Gbp2b/Gbp1 and Gbp5 in skin of uninfected and infected mice. Expression of Gbp2b/Gbp1 (A) and Gbp5 (B) in skin of uninfected and infected female mice of strains BALB/c (9 infected and 7 uninfected), STS (7 infected and 6 uninfected), CcS-5 (6 infected and 6 uninfected), CcS-16 (6 infected and 6 uninfected), CcS-20 (6 infected and 6 uninfected), O20 (10 infected and 7 uninfected), B10 (8 infected and 6 uninfected), B10.O20 (13 infected and 5 uninfected), OcB-9 (7 infected and 6 uninfected), and OcB-43 (9 infected and 6 uninfected) were compared. Animals were subcutaneously inoculated with 10⁷ promastigotes of Leishmania major. Control, uninfected mice were kept in the same animal facility. Both groups were killed in the same time—after 8 weeks of infection or start of experiment. The data show the means ± SD. Nominal P values are shown.