Table 3.

CMR Mapping Parameters

	Healthy controls (n = 20)	Acute viral myocarditis (n = 20)	IIM with inflammatory myocarditis (n = 20)	p-value / age adjusted p-value
Myocardium including LGE positive segments
T1 native, ms	965 ± 25	1044 ± 63*/*	1017 ± 43*/*	0.121
T1 contrast 15 min, ms	379 ± 54	320 ± 34*/*	326 ± 54*/*	0.925
ECV, %	22 ± 3	24 ± 7*/*	23 ± 3	0.134
T2, ms	48 ± 2	53 ± 4*/*	53 ± 3*/*	0.758
Myocardium excluding LGE positive segment
T1 native, ms	965 ± 25	1023 ± 52*/*	1011 ± 36*/*	0.445
T1 contrast 15 min, ms	379 ± 54	330 ± 38*/*	328 ± 51*/*	0.718
ECV, %	22 ± 3	25 ± 3*/*	23 ± 4	0.351
T2, ms	48 ± 2	51 ± 3*/*	52 ± 3*/*	0.174
Skeletal Muscles
T1 native, ms	842 ± 39	844 ± 62	963 ± 127*/*	0.001 / 0.002
T1 contrast 15 min, ms	510 ± 43	482 ± 39*/*	374 ± 55*/*	< 0.001 / < 0.001
ECV, %	10 ± 2	10 ± 3	19 ± 7*/*	< 0.001 / < 0.001
T2, ms	40 ± 2	38 ± 2*	45 ± 10	< 0.001 / 0.022

Values are mean ± SD. */* p < .05 compared to controls without / with age adjustment. p-values/age adjusted p-values of the direct comparison between acute viral myocarditis and IIM myocarditis are shown in the last column, using Mann-Whitney U test and a multivariate regression model. Age adjusted p-values were only calculated in case of significant non-adjusted p-values

IIM idiopathic inflammatory myopathy, ECV extracellular volume fraction, SD Standard deviation