Table 1.
Core Structure Candidates Used in ASTP Fabrication
| particle core | approx. Mw in kDa (g·mol−1) | approx. # Ab per particle | ASTP Mw in kDaa (g·mol−1) | selector attachment mode | |
|---|---|---|---|---|---|
| protein A/G | 50–60 | 2–5 | 380–1250 | adsorption | affinity |
| Ficoll | average 400 | 1–6 | 560–1360 | covalent | Schiff base |
| IgG (mAb) | ~160 | 1 | 320–480 | adsorption | affinity |
| HPCb | ~2000 | 1–10 | 2200–3600 | adsorption | affinity |
a
This refers to the approximate gram Mw of the selector/core complex in kilodaltons.
b
HPC is an abbreviation for hydrophilic polymer core.