FIGURE 5.

Mean tumor cell density of biopsies vs mean fluorescence intensities as measured spectrometrically, stratified by 5-ALA dose (all localizations including normal brain, all fluorescence qualities, values for single fluorescence qualities in single patient averaged). A, 0.2 mg/kg b.w. B 2 mg/kg b.w. C 20 mg/kg b.w. We only found a relationship between tumor cell density and fluorescence for the 20 mg/kg group. The mean fluorescence intensities per treatment group were 0.767 ± 0.0564 a.u. (0.2 mg/kg); 0.245 ± 0.340 a.u. (2 mg/kg); and 1.71 ± 1.65 a.u. (20 mg/kg; P < .0001 by analysis of variance).