Table 2: Summary of Results From the DEFER Study.

Year	Patients (n)	Participants	Endpoint	FFR cut-off	Adenosine	Mean FFR	Treatment	Event-free survival	Primary endpoint P value
2007	325 [comprising: 181 With FFR ≥0.75 randomised to PCI or Defer; 144 with FFR <0.75 allocated to registry]	Stable angina patients scheduled for PCI with single-vessel disease	Event-free survival	Defer if FFR ≥0.75	IV (140 μg/kg/min) or IC (15 μg in the RCA or 20 μg in the LCA)	Defer (n=91): 0.87±0.07 Perform (n=90): 0.87±0.06 Registry (n=144): 0.56±0.16	PCI/BMS versus FFR-guided deferral	Defer group (n=91) 79 % Perform group (n=90) 73 %	0.52

BMS = bare-metal stent; FFR = fractional flow reserve; IC = intracoronary; IV = intravenous; LCA = left coronary artery; PCI = percutaneous coronary intervention; RCA = right coronary artery. Source: Pijls, et al. 2007.