Table 4: Summary of Results From the COURAGE Trial.
Year | Patients (n) | Participants | Primary outcome | Assigned groups, (patients [n]) | Follow-up duration | PCI treatment | Primary outcome (events [n]) | Hazard ratio for PCI (95 % CI) | P value | ||
---|---|---|---|---|---|---|---|---|---|---|---|
PCI + OMT | OMT alone | OMT plus routine PCI | OMT plus bailout PCI | ||||||||
2007 | 2,287 of 35,539 patients screened | Stable angina or objective evidence of ischaemia or angina with coronary stenosis ≥80 % | Death from any cause Non-fatal MI | 1,149 (total randomised) 1,077 (PCI attempted) | 1,138 | Median: 4.6 years (IQR 3.3–5.7) | BMS (n=1.046) (97 %) DES (n=31) (3 %) | 211 | 202 | 1.05 (0.87–1.27) | 0.62 |
BMS = bare-metal stent; DES = drug-eluting stent; IQR = interquartile range; MI = myocardial infarction; OMT = optimal medical therapy; PCI = percutaneous coronary intervention. Source: Boden, et al. 2007