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. 2018 Feb 12;11:35. doi: 10.1186/s13068-018-1031-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Time course of fed-batch cultivation. Fermentation was performed in 5-L Bioflo320 bioreactor with 2 L initial YPD media. 1 L of 500 g/L glucose was fed to bioreactor after glucose depletion