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. Author manuscript; available in PMC: 2018 Feb 12.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Apr 23;7(6):759–778. doi: 10.1002/wnan.1346

FIGURE 10.

FIGURE 10

Nontoxic quantum dots (QDs) for stem cell imaging and delivery of nucleic acids. (a) Novel synthesis of ZAIS (Zn, Ag, In, and S) QDs using a sonochemical approach to tune emission properties based on the ratio of starting elements. (b) A library of ZAIS QDs synthesized by varying elemental composition. (c) Cell viability of novel ZAIS QDs compared to conventional CdSe QDs shows that ZAIS QDs are nontoxic to human mesenchymal stem cells (hMSCs). (d) ZAIS QDs are effectively internalized by hMSCs and show a strong fluorescence signal, thus making ZAIS QDs suitable for stem cell tracking applications. (Reprinted with permission from Ref 72. Copyright 2012 John Wiley and Sons)