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. Author manuscript; available in PMC: 2018 Feb 12.
Published in final edited form as: ACS Nano. 2015 Apr 8;9(4):3780–3790. doi: 10.1021/nn5066028

Figure 1.

Figure 1

Schematic diagram illustrating control over the differentiation of adipose-derived stem cells using combinatorial graphene hybrid-pattern arrays. The scheme represents the steps taken to modulate the morphology of hADMSCs (adipose tissue from 29- and 63-year-old-female patients) using NGO patterns and to guide differentiation based on the physico-chemical characteristics of NGO. This method resulted in enhanced differentiation into osteoblasts and neurons in a selective and efficient way. Fluorescence images shown are F-actin-stained hADMSCs whose morphologies were controlled by NGO line and grid patterns in combination with PEG-containing passivation molecule. Scale bar = 100 μm.