Figure 14.
Active-site regions of quinone-containing disulfide catalysts. Quinone-proximal disulfides are shown as spheres with sulfur atoms in yellow and Cβ atoms in green. The quinone (orange sticks) is buried in the core of the helical bundle in each enzyme, and the amino-terminal cysteine of the quinone-proximal disulfide (S1) is exposed to in-line nucleophilic attack. PDB codes are 2ZUP and 3KP9.