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. 2018 Feb;94:1–7. doi: 10.1016/j.jclinepi.2017.10.016

Table 3.

Stratified and Mantel-Haenszel adjusted odds ratios for the association between trial enrolment and mortality

Patient characteristic Stratum specific odds ratio (95% CI) M-H summary odds ratio (95% CI) P-value chi-square test P-value test for interaction
Observational cohort 14/1,140 0.40
Clinical trial cohort 4/527
Age 12–59 mo 0.0 (–) 0.7 (0.2, 2.0) 0.46 0.22
Age 2–11 mo 0.9 (0.3, 3.0)
Female 1.2 (0.3, 5.2) 0.6 (0.2, 1.9) 0.38 0.18
Male 0.2 (0.0, 1.9)
Immunization not up to date 0.0 (–) 0.6 (0.2, 1.9) 0.38 0.37
Immunization up to date 0.7 (0.2, 2.3)
Duration of symptoms < 3 days 0.0 (–) 0.6 (0.2, 1.9) 0.38 0.37
Duration of symptoms ≥3 days 0.7 (0.2, 2.3)
Weight-for-age Z score ≥2SD 0.5 (0.1, 2.2) 0.7 (0.2, 2.3) 0.58 0.31
Weight-for-age Z score <−2SD 1.7 (0.2, 12.3)
No history of wheeze 0.6 (0.2, 2.5) 0.8 (0.2, 2.7) 0.66 0.44
History of wheeze 0.0 (–)
Pallor absent 0.8 (0.3, 2.7) 0.7 (0.2, 2.1) 0.48 0.32
Pallor present 0.0 (–)
Dehydration absent 0.5 (0.1, 1.8) 0.7 (0.2, 2.0) 0.47 0.20
Dehydration present 3.3 (0.2, 54.9)
District hospital 1.3 (0.3, 5.1) 0.6 (0.2, 1.8) 0.38 0.15
Provincial hospital 0.2 (0.0, 1.8)

Abbreviation: CI, confidence interval.