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. Author manuscript; available in PMC: 2018 Jul 13.
Published in final edited form as: Vaccine. 2017 Jun 9;35(32):3974–3981. doi: 10.1016/j.vaccine.2017.05.093

Table 2.

Key parameters in the agent-based model.

Parameter % Vaccine received (%)
Range
Reference
LAIV IIV-IM IIV-ID No. Minimum Maximum
Coverage by age, years
 6–23 months 70.4 0.0 100.0 0.0 69.6 71.2 Adapted from [38,39]
 2–4 68.1 52.0 48.0 0.0 67.3 68.9
 5–8 61.0 52.0 48.0 0.0 60.2 61.8
 9–17 52.9 52.0 48.0 0.0 52.1 53.7
 18–49 32.3 2.0 97.0 1.0 31.9 32.7
 50–64 45.3 0.0 99.0 1.0 44.9 45.7
 65–106 65.0 0.0 100.0 0.0 64.6 65.4
LAIV contraindications by age, years
 2–4 8.8 [40]
 5–17 1.0
Absolute vaccine coverage increases with choice 6.5 3.25 11.25 [1]
Vaccine cost, US$
 IIV-IM 10.69 0.00 21.38 [41]
 LAIV 23.70 0.00 47.40
 IIV-ID 15.69 0.00 31.38
Vaccine administration cost, US$ 25.08 [28]
Increased cost of choice 5.0 2.5 7.5 [42]
Latent period, daysa 1.9 1 2 [17,2025,43]
Infectious period, daysa 4.1 3 6
Asymptomatic rateb 33.0
Asymptomatic reduction in infectivityc 50.0
Symptomatic absenteeismb 50.0
Vaccine effectivenessb 59.0 [44]

IIV = inactivated influenza vaccine; LAIV = live attenuated influenza vaccine; IM = intramuscular; ID = intradermal.

a

Drawn from a truncated Weibull distribution with the listed nominal (mean), minimum and maximum values.

b

Probability point estimate that does not vary across simulations; within each simulation, it is the action potential threshold above which an outcome (i.e., exhibit symptoms, stay home from work, or vaccine protects against disease) occurs and below which it does not.

c

A constant that does not vary across simulations.