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. Author manuscript; available in PMC: 2018 Feb 12.
Published in final edited form as: Biochem Biophys Res Commun. 2016 Sep 3;478(4):1706–1712. doi: 10.1016/j.bbrc.2016.09.008

Fig. 2. MS-5 cell POSTN supports MB-1 niche-dependent myeloblastoma cells.

Fig. 2

(A, D) The number of MB-1 cells cocultured with MS-5 cells decreased in the presence of anti-mPOSTN Ab (A), and increased in the presence of excess amount of exogenous rmPOSTN (D).

(B, E) Mitogenicity of MB-1 cells, cocultured with MS-5 cells, measured by BrdU incorporation, was attenuated in the presence of anti-mPOSTN Ab (B), and slightly increased in the presence of excess amount of exogenous rmPOSTN (E).

(C, F) The number of cobblestone areas per visual field formed by MB-1 cells cocultured with MS-5 cells was counted. The number decreased in the presence of anti-mPOSTN Ab (C), but was unchanged when excess amount of exogenous rmPOSTN was added (F).

N = 3 (A, E), 8 (B), or 4 (C, D, F).