Fig 5. A highly-variable cell cycle phase is preserved between multi-checkpoint DDT models.

Relative variability in checkpoint passage times, as quantified by the coefficient of variation (CV), is shown for each phase of the DDT2 and DDT3 models for all experimental conditions considered. Note that the phase numbers are arbitrary (ordered from largest to smallest CV) and do not reflect their actual order in the cell cycle (see “Stochastic checkpoint models”). Hereafter, the high-variability phase is referred to as “H” and the low-variability phase(s) as “L” (L1 and L2 for DDT3).