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. 2018 Feb 12;13(2):e0192701. doi: 10.1371/journal.pone.0192701

Table 1. Physiological effects of chronic CORT treatment.

LMEs for body mass, hematocrit (Ht %), redox state markers (TAS—total antioxidant status, UA—uric acid, tGSH—total glutathione, MDA—malondialdehyde; for residual TAS, see Methods) and coccidian infestation, and GLMMs for innate immunity variables (natural antibodies [NAbs] by hemagglutination score and complement by hemolysis scores). Degrees of freedom are 1 for treatment and 3 for sampling and treatment × sampling throughout. Significant effects are marked in boldface and marginally significant effects (0.05 < P ≤ 0.10) in italic.

Response Treatment (T) Sampling (S) T × S
χ2 P χ2 P χ2 P
Body mass 1.30 0.254 12.10 0.007 6.02 0.111
Ht % 84.45 < 0.001 13.54 0.001 69.28 < 0.001
TAS 0.01 0.942 5.99 0.112 1.22 0.748
Residual TAS 0.00 0.962 4.69 0.196 0.97 0.809
UA 0.01 0.924 17.98 < 0.001 1.51 0.681
tGSH 2.75 0.097 10.31 0.016 6.57 0.087
MDA 0.00 0.961 5.86 0.118 4.62 0.202
Coccidiosis 0.73 0.394
NAbs 4.01 0.260 15.12 0.010 2.96 0.398
Complement 2.63 0.105 25.64 < 0.001 7.05 0.070