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. Author manuscript; available in PMC: 2018 Feb 12.

Published in final edited form as: Methods Enzymol. 2017 Jul 14;593:405–448. doi: 10.1016/bs.mie.2017.05.005

Human sequence alignments of Rho, β2-AR, μ-OR, LPAR1, S1PR1, CB1, CB2 and GPR3 receptors. A) Transmembrane helix 1 (TMH1); B) TMH2; C) TMH3; D) TMH4; E) EC2 loop; F) TMH5; G) TMH6; H) TMH7. Color code: red: prolines; yellow: highly conserved residues; pink: cysteines in an internal disulfide bridge; blue: cysteines in non-internal disulfide bridge; purple: particular motif.

Human sequence alignments of Rho, β2-AR, μ-OR, LPAR1, S1PR1, CB1, CB2 and GPR3 receptors. A) Transmembrane helix 1 (TMH1); B) TMH2; C) TMH3; D) TMH4; E) EC2 loop; F) TMH5; G) TMH6; H) TMH7. Color code: red: prolines; yellow: highly conserved residues; pink: cysteines in an internal disulfide bridge; blue: cysteines in non-internal disulfide bridge; purple: particular motif.