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. Author manuscript; available in PMC: 2018 Feb 12.
Published in final edited form as: Invest New Drugs. 2016 Dec 21;35(3):290–297. doi: 10.1007/s10637-016-0418-8

Table 4.

At least possibly related to treatment grade ≥ 2 adverse events experienced by at least 3 patients

Adverse Event * Patients (N=29)
Grade 2
n (%)
Grade 3
n (%)
Grade 4
n (%)
Overall
n (%)
Anemia 9 (31) 3 (10.3) 0 12 (41.4)
Fatigue 10 (34.5) 0 0 10 (34.5)
Anorexia 9 (31) 0 0 9 (31)
Hypoalbuminemia 6 (20.7) 2 (6.9) 0 8 (27.6)
Hypophosphatemia 2 (6.9) 5 (17.2) 0 7 (24.1)
Nausea 6 (20.7) 1 (3.4) 0 7 (24.1)
Mucositis 5 (17.2) 1 (3.4) 0 6 (20.7)
Vomiting 3 (10.3) 2 (6.9) 0 5 (17.2)
Diarrhea 4 (13.8) 1 (3.4) 0 5 (17.2)
Hypokalemia 4 (13.8) 1 (3.4) 0 5 (17.2)
Hypertension 2 (6.9) 3 (10.3) 0 5 (17.2)
Dyspnea 2 (6.9) 2 (6.9) 0 4 (13.8)
Leukopenia 2 (6.9) 1 (3.4) 1 (3.4) 4 (13.8)
Abdominal pain 1 (3.4) 2 (6.9) 0 3 (10.2)
Dehydration 2 (6.9) 1 (3.4) 0 3 (10.2)
Hyperglycemia 2 (6.9) 1 (3.4) 0 3 (10.2)
Hyponatremia 0 3 (10.3) 0 3 (10.2)
Neutropenia 1 (3.4) 0 2 (6.9) 3 (10.2)
Thrombocytopenia 3 (10.3) 0 0 3 (10.2)
*

No Grade 5 Adverse Events were noted