Table 2. Linear regression models for Wechsler Intelligence Scale for Children-IV (WISC-IV) outcomes (n=106).
| Full Scale IQa Beta (95% CI) | Perceptual Reasoningb Beta (95% CI) | Processing Speedc Beta (95% CI) | Working Memoryd Beta (95% CI) | Verbal Comprehensione Beta (95% CI) | |
|---|---|---|---|---|---|
| Model 1: Single biomarker models | |||||
| Log Hair Mn | −1.91* (−3.68, −0.14) | −0.88 (−3.08, 1.32) | −1.53 * (−3.03, −0.03) | −2.28 * (−4.31, −0.25) | −1.24 (−3.17, 0.68) |
| Log Blood Mnf | 3.49 (−6.65, 13.63) | 3.46 (−5.88, 12.80) | 2.08 (−5.72, 9.90) | 7.12 (−4.14, 18.37) | −3.37 (−14.09, 7.36) |
| Log Blood Pb | −2.71 (−5.85, 0.44) | −1.66 (−5.25, 1.94) | −2.14 (−4.95, 0.66) | −0.86 (−4.95, 3.22) | −1.90 (−5.50, 1.71) |
| Log Serum Cotinine | −0.42 (−1.57, 0.74) | −0.79 (−2.19, 0.60) | −0.63 (−1.67, 0.41) | −0.67 (−2.17, 0.83) | 0.76 (−0.76, 2.28) |
| Model 2: Log hair Mn sex stratified models | |||||
| Female, Log Hair Mn | −2.24 (−4.88, 0.39) | −2.16 (−5.24, 0.92) | −2.16 (−4.61, 0.29) | −2.18 (−5.22, 0.87) | −0.81 (−3.66, 2.04) |
| Male, Log Hair Mn | −1.55 (−4.20, 1.10) | 0.59 (−2.71, 3.90) | −1.59 (−3.25, 0.07) | −2.70 (−5.51, 0.11) | −0.63 (−3.36, 2.10) |
| Model 3: Multiple biomarkers models | |||||
| Log Hair Mn | −1.49 (−3.48, 0.48) | −0.16 (−2.66, 2.33) | −1.14 (−3.00, 0.72) | −1.94 (−4.52, 0.64) | −1.84 (−4.07, 0.40) |
| Log Blood Mnf | 1.71 (−7.90, 11.32) | 3.36 (−6.35, 13.08) | 0.72 (−7.13, 8.56) | 5.95 (−6.36, 18.24) | −5.37 (−14.79, 4.05) |
| Log Blood Pb | −2.58 (−6.10, 0.94) | −1.02 (−5.08, 3.03) | −1.60 (−4.73, 1.53) | 0.72 (−3.43, 4.87) | −2.80 (−6.63, 1.02) |
| Log Serum Cotinine | 0.20 (−1.09, 1.50) | −0.70 (−2.37, 0.96) | −0.14 (−1.36, 1.07) | −0.54 (−2.18, 1.09) | 1.66* (0.05, 3.26) |
*
p-value < 0.05
a
Covariates include parent IQ and Scholastic Satisfaction T score;
b
Covariates include parent IQ and home ownership;
c
Covariates include parent IQ, income, birth weight, and Communication T score;
d
Covariate includes parent IQ;
e
Covariates include Parent IQ, income, and Scholastic Satisfaction T score;
f
Serum ferritin also included in models with blood Mn