Figure 1. WD consumption produces an obese-like state.
Mice fed the ‘western’ diet (WD) A) gained significantly more weight and B) consumed significantly more calories than mice fed the control standard diet (SD). C,D) Although the insulin tolerance test (ITT) at week 12 found no effect of diet, E,F) the glucose tolerance test (GTT) at week 16 revealed significantly impaired glucose tolerance in WD mice. n = 7-12; p** < 0.01, p*** < 0.001 vs. SD.