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. Author manuscript; available in PMC: 2019 Jan 21.
Published in final edited form as: Neuroscience. 2017 Dec 28;372:1–15. doi: 10.1016/j.neuroscience.2017.12.036

Figure 8. WD consumption disrupts mu-opiod receptor (MOPr) plasticity in the dorsal striatum.

Figure 8

A) Time series of electrically-evoked EPSC (eEPSC) averages over the 40 min recording session. B) Application of the MOPr agonist DAMGO (0.3 μM) did not reveal overall diet group differences in response to DAMGO. However, an examination of cell groupings C) revealed that there was a significant lack of response to DAMGO in WD cells. n = 11-13 cells; 2 mice per condition. p* < 0.05 for adjusted residual analysis relative to expected distribution.