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. 2018 Feb 12;8:2856. doi: 10.1038/s41598-018-21254-8

Table 2.

Thickness of retinal layers.

Thickness
GCL IPL INL OPL ONL Total
Sham before 19.86 ± 0.95 46.33 ± 1.38 22.13 ± 1.19 16.97 ± 1.14 69.27 ± 2.65 174.58 ± 4.26
Sham after 20.90 ± 1.36 46.32 ± 1.50 20.93 ± 1.50 15.93 ± 0.91 65.52 ± 2.32 169.60 ± 4.42
ICP before 21.88 ± 1.31 46.06 ± 1.89 19.63 ± 1.10 16.74 ± 1.12 59.02 ± 2.23 163.33 ± 3.00
ICP after 18.97 ± 0.87 50.35 ± 2.41 19.64 ± 1.53 19.12 ± 1.03 56.45 ± 2.44 164.54 ± 3.48

Thickness values are expressed as mean µM ± SEM. N = 6 eyes in each group. For each eye, SD-OCT was used to calculate the thickness of each retinal layer at the start of the experiment (Sham before and ICP before). This was compared to the thickness of each layer in the same eye after 2 weeks (Sham after and ICP after) with a t-test. The only difference detected in any retinal layer was a reduction in the thickness of the GCL after 2 weeks of ICP elevation (bold, p = 0.037). SD-OCT = Spectral domain optical coherence tomography; ICP = intracranial pressure; GCL = retinal ganglion cell layer; IPL = inner plexiform layer; INL = inner nuclear layer; OPL = outer plexiform layer; ONL = outer nuclear layer.