Table 3.

Relative HIF-1α intensity in each retinal layer.

	GCL	IPL	INL	OPL	ONL
Sham	1 ± 0.17	1 ± 0.16	1 ± 0.15	1 ± 0.27	1 ± 0.19
Elevated ICP	2.21 ± 0.37	1.19 ± 0.09	1.32 ± 0.29	1.26 ± 0.3	2.09 ± 0.86

Normalized intensity is expressed as mean ± SEM. N = 4 sections from 4 eyes in each group. After 2 weeks, Sham and ICP elevation eyes were assessed with antibody to HIF-1α and the mean normalized staining intensity compared with a t-test. The only statistically significant difference detected in any retinal layer was in the GCL (bold, p = 0.042). HIF = hypoxia-inducible factor; ICP = intracranial pressure; GCL = retinal ganglion cell layer; IPL = inner plexiform layer; INL = inner nuclear layer; OPL = outer plexiform layer; ONL = outer nuclear layer.