Table 2.
Characteristics of the clusters identified based on the 51 most differentially expressed miRNAs.
Cluster | No. of GSC cultures | No. of non-stem cell cultures | Multilineage differentiation‡ | Tumorigenicity |
---|---|---|---|---|
IA | 6 | 0 | 4/4** | 5/5 |
IB | 4 | 2 | 0/3 | 2/3 (GSC) 1/2 (non-stem cells) |
II | 0 | 8 | n.d. | 5/6 |
‡Number of cell cultures exhibiting pronounced differentiation in serum containing media/number of analyzed cell cultures, **P < 0.05, Pearson’s chi-squared test compared to cluster IB, n.d. - not determined.