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. 2018 Feb 8;9:192. doi: 10.3389/fimmu.2018.00192

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Copyright © 2018 Parmar, Patel, Yadav, Parikh, Patel, Mohankrishnan, Bhurani, Joshi and Dalai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Assessment of liver microenvironment through whole-genome RNA Seq. (A) Heat map showing differential gene expression in mouse liver post 72 h following 50K radiation-attenuated sporozoites (RAS) or 10K infectious sporozoites (Inf. Spz) inoculation. (B) Enriched pathway in Kyoto Encyclopedia of Genes and Genomes (KEGG) database: significantly differentially expressed genes identified by KEGG as involved in toll-like receptor signaling and interferon signaling. Red, significantly increased expression (fold change > 1); grey, unchanged expression.