Table 2.

Summary of HIV-1 viral blocking data. 10,000 TZM-bl cells or PBMCs were incubated with 200TCID50 HIV-1 and HIV-1 infection was measured 48-72 hours later. Assays were set up in quadruplicate and repeated at least 3 times with the listed viral strains, unless otherwise indicated.

Protein	Name	Live virus TZM-bl cells (mean and range HIV-1 inhibition)§	Live virus PBMCs (mean and range HIV-1 inhibition)#
Blank Control	Cc-Control	% infection: 110.1% Range 80.8%–137.7%	% infection: 100% Range 99.9%–100%
BmKn2	Cc-BmKn2	38.3% (14.1%–84.3%)	78% (61.2%–83.5%)
α-1-antitrypsin	Cc-A1AT	39.6% (9.9%–87.8%)	56.2% (28.1%–73.6%)
Elafin	Cc-Elafin	44.8% (15.5%–80.4%)	76.5% (57.7%–80.2%)
Indolicidin	Cc-Indolicidin	20.6% (2.2%–52.7%)	100%*

^§Presented mean and range is a summary of data from HIV-1 strains 89.6, BaL, JR-FL, pykJR-CSF.

^#Presented mean and range is a summary of data from HIV-1 strains 89.6, JR-FL, SF162.

*Performed in quadruplicate with HIV-189.6.