Table 1.

List of the alignment methods and presents their features

Short name	Full name	Technique	Target function	Peak picking based	NP	SW	Pair-Wise(#)	Correction method	Software	Remarks
COW	Correlation Optimized Warping (Nielsen et al. 1998)	Dynamic programming	Pearson correlation coefficient	No	2	Yes	Yes	Insert and deletion	(1)	Slow
PABS	Peak alignment by Beam search (Lee and Woodruff 2004)	Beam search algorithm	Pearson correlation coefficient	No	3	Yes	Yes	Shift & Insert and deletion	(+)
FW	Fuzzy Warping (Wu et al. 2006a)	Fuzzy logic for matching most intense peaks	Maximize fuzzy membership Gaussian function	Yes	1	No	Yes	Insert and deletion	(4)
icoshift	Interval correlation shifting (Savorani et al. 2010)	Segmentation model by equal size segments or manually selecting segments	FFT cross-correlation	No	2	Yes	Yes	Shift & Insert and deletion	(6)	The peak-piking step adds complexity