Table 5.
Univariate analysis of lymph node metastasis and clinicopathological features in PTMC
| Characteristic | LNM− | LNM+ | χ 2 | P |
|---|---|---|---|---|
| Gender | ||||
| Female | 573 | 227 | 15.289 | <0.001 |
| Male | 119 | 88 | ||
| Age (years) | ||||
| ≥45 | 406 | 152 | 9.506 | 0.002 |
| <45 | 286 | 163 | ||
| Subtypes | ||||
| CPTMC | 296 | 175 | 14.986 | 0.001 |
| FPTMC | 332 | 122 | ||
| EnPTMC | 64 | 18 | ||
| Fibrosis | ||||
| Absent | 9 | 6 | 0.538 | 0.463 |
| Present | 683 | 309 | ||
| Calcification | ||||
| CPTMC | ||||
| Absent | 232 | 119 | 6.239 | 0.012 |
| Present | 64 | 56 | ||
| FPTMC | ||||
| Absent | 232 | 76 | 2.352 | 0.125 |
| Present | 100 | 46 | ||
| EnPTMC | ||||
| Absent | 24 | 5 | 0.581 | 0.446 |
| Present | 40 | 13 | ||
| Minimal ETE | ||||
| Absent | 585 | 222 | 26.890 | 0.000 |
| Present | 107 | 93 | ||
| Coexistence of HT | ||||
| Absent | 505 | 237 | 0.571 | 0.450 |
| Present | 187 | 78 | ||
| Multifocality | ||||
| Absent | 474 | 169 | 20.671 | 0.000 |
| Present | 218 | 146 | ||
| Tumor size | ||||
| >5 mm | 311 | 199 | 28.788 | 0.000 |
| ≤5 mm | 381 | 116 | ||
CPTMC conventional variant PTMC, FPTMC follicular variant PTMC, EnPTMC encapsulated variant PTMC, minimal ETE minimal extrathyroidal extension, HT Hashimoto’s thyroiditis, LNM lymph node metastases