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Cytokine expression in ischemic hind limb. IL-12 (A), IL-10 (B), IL-6 (C), and monocyte chemoattractant protein (MCP)-1 (D) protein concentrations in ischemic limb of wild-type (WT), p40−/−, and p35−/− mice fed a chow diet or a high-fat diet (HFD) were quantified by enzyme-linked immunosorbent assay. Data are expressed as means ± SEM (A–D). n = 5 to 6 (A–D). ∗P < 0.05 versus WT; †P < 0.05 versus WT HFD or WT; ‡P < 0.05 versus WT HFD.
